What is Saxenda?
Saxenda (Liraglutide) is an INJECTABLE medicine
to help those with:
- Excess weight (BMI > 27)
weight related medical problem
It should be used with a reduced-calorie meal plan
and increased physical activities
Saxenda was clinically tested and proven in a study of 3,731 patients
in which 85% of people taking Saxenda lost some weight.
How does it work?
Saxenda is part of a medication class called glucagon-like peptide-1 (GLP-1) agonists. GLP-1 is a gut hormone that plays an important role in regulating your appetite and how your body handles sugar. GLP-1 agonists, like Saxenda, mimic this hormone’s effects.
In particular, it helps promote weight loss by slowing gastric emptying after meals. This means that food stays in your stomach longer, causing you to feel full. But this effect is also why Saxenda can upset your stomach. We’ll discuss this further below.
What are the side effects?
It’s important to review possible side effects with your healthcare provider. They can give you tips for how to manage them, and what to look for if it’s something more serious. Read more about the common and serious side effects below.
Common side effects
As previously discussed, Saxenda slows down the movement of food through your stomach. This can upset your stomach, causing nausea and vomiting, diarrhea, or constipation. It can also cause indigestion and abdominal pain.
These stomach-related side effects are most common when you first start taking Saxenda, and with dose changes. That’s why your dose is usually adjusted slowly over several weeks to minimize these side effects.
Other common side effects include:
Pain at the injection site
What’s the average weight loss on Saxenda?
Saxenda has been studied in adults with and without Type 2 diabetes, as well as adolescents. These studies were conducted over the course of 56 weeks and compared Saxenda to a placebo (an injection without medication).
In one study, adults with Type 2 diabetes lost an average of 5% to 6% of their initial body weight. People taking Saxenda lost about 3% to 4% more weight than people taking a placebo.
In another study, adults without Type 2 diabetes lost an average of 8% of their initial body weight. This was about 5% more weight loss than the placebo group.
During the adolescent study, people in the Saxenda group lost almost 3% of their initial body weight. This was 5% greater weight loss than the placebo group, since those participants actually gained weight.
As the studies show, Saxenda can help you successfully lose weight. But keep in mind, It works best when taken in combination with a reduced-calorie diet and exercise.